Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| F64950 | F64950 | U.K. | 2001 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT | 68 |
| 2 | 3TC+AZT+NFV | 15 |
| 3 | 3TC+AZT+NVP | 118 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | K103KN, G190GA | V35T, E36A, T39E, S48T, E53D, K101X, K122E, D123S, E138A, K173T, Q174K, T200A, E203A, Q207E, R211K, F214L, V245Q, E248N, D250E, A272P, K275R, Q278H, E291D, V292I, I293V, V317A, I329V | I135LP |
| >F64950| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPDNPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLXKNKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSLNNATPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPDIVI YQYVDDLYVASDLEIGQHRAKIAELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPNKESWTVNDIQKLVGKLNWASQIYPGIRVKHLCKLLRGTKALTDIVPLTEEAE LELAENREILKEPVHGAYYDPSKDLIAEVQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, M36I, R41K, D60E, L63LP, H69K, L89IM, I93L |
| >F64950| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYE QIPIEICGKKAIGTVLVGPTPVNIIGRNILTQLGCTLNF |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |