Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| M72003 | M72003 | U.K. | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+ AZT | 3 |
| 2 | NFV+ 3TC+ AZT | 92 |
| 3 | NVP+ IDV+ D4T+ DDI+ RTV | 120 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R | K219E | G190S | L26X, T27X, E28EA, K30X, V35T, E36A, T39E, S48T, K101KQ, K122E, I135V, K166R, K173T, D177E, T200A, E203K, Q207E, V245Q, D250E, A272P, V292I, I293V, E297EA, D324E | W24WL |
| >M72003| codons 24-333 LPXXAEXIKALTAICEEMEKEGKITKIGPENPYNTPVFAIKKKNSTRWRKLVDFRELNKR TQDFWEVQLGIPHPAGLQKKKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSVNNETPGIR YQYNVLPQGWKGSPAIFQSSMTRILEPFRTQNPEIVIYQYMDDLYVSSDLEIGQHRAKIK ELREHLLRWGFTTPDEKHQKEPPFLWMGYELHPDKWTVQPIQLPEKESWTVNDIQKLVGK LNWASQIYPGIKVKQLCKLLRGTKALTEIVPLTAEAELELAENREILKEPVHGVYYDPSK ELIAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54IV, L90M | L10F | I13V, K14N, I15V, L19I, K20T, E35N, M36I, R41K, K45R, I62IV, L63P, I64V, H69K, K70R, T74S, L89M, I93L |
| >M72003| codons 1-99 PQITLWQRPFVTVNVGGQITEALLDTGADDTVLENINLPGKWKPRMIGGIGGFVKVRQYD QVPVEICGKRAIGSVLVGPTPVNIIGRNMMTQLGCTLNF |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |