Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| M76115 | M76115 | U.K. | 2002 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+ DDI+ NVP | 130 |
| 2 | LPV+ AZT+ 3TC+ ABC+ TDF | 19 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Q151M | F116Y | G190A | E6K, V35T, T39A, F87S, K122E, D123S, E169D, Q174K, D177E, V179I, Q207A, R211S, H221Y, V245T, K277R, K281R, L283I, E291D, I293V, P294T |
| >M76115| codons 1-296 PISPIKTVPVKLKPGMDGPKVKQWPLTEEKIKALTEICAEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDSWEVQLGIPHPAGLKKKKSVTVLDVGDAYYSVPL DESFRKYTAFTIPSINNETPGIRYQYNVLPMGWKGSPAIFQSSMTKILDPFRKKNPEIII YQYMDDLYVASDLEIGQHRTKIEELRAHLLSWGFTTPDKKYQKEPPFLWMGYELHPDKWT VQPITLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCRLIRGTKALTDVVTLT |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, I15V, E35D, M36I, N37E, R41K, K45R, R57K, H69K, L89M |
| >M76115| codons 1-99 PQITLWQRPLVTVKVGGQLKEALLDTGADDTVLEDIELPGKWKPRMIGGIGGFIKVKQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |