Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| F76135 | F76135 | U.K. | 2000 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | D4T+ RTV+ EFV+ ABC | 65 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| Q7QH, T12V, K14R, K20R, E21K, E35D, M36I, N37D, R41K, R57K, L63V, H69K, L89M |
| >F76135| codons 1-99 PQITLWHRPLVVIRIGGQLRKALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVKQYD QIVIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R | K219Q | K103N | V35T, S48T, V60I, K122E, I135T, K173V, Q174K, D177E, I178M, Q207A, R211S, D218DE, K238KQ, V245E, D250E, K281R, T286A, E291D, I293V, P294T |
| >F76135| codons 1-324 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKITKIGPENPYNTPI FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DEDFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRVKNPEMVI YQYMDDLYVGSDLEIGQHRTKIEELRAHLLSWGFTTPEQKHQKEPPFLWMGYELHPDQWT VQPIELPEKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGAKALTDVVTLTEEAE LELAENREILKEPVHGVYYDPSKD |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |