<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
F68541 F68541 U.K. 2002 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 3TC+AZT+NFV 198

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V       V21VI, V35T, E36A, T39E, S48T, D121H, K122E, K173T, Q174K, D177E, Q207E, R211K, F214FL, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, V317A, I326V  
>F68541| codons 1-333
PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
HEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEIVI
YQYVDDLYVGSDLEIGQHRTKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGAYYDPSKDLVAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46MI, L90M   T12S, I13V, I15V, L19I, K20T, E35X, M36I, R41K, H69K, T74AS, L89I, I93L  
>F68541| codons 1-99
PQITLWQRPLVSVKVGGQITEALLDTGADDTVLEXINLPGKWKPKIIGGIGGFIKVRQYD
QILIEICGKKAIGAVLVGPTPVNIIGRNIMTQLGCTLNF

References
Author Title Citation
Weber, J Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005