Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| F68541 | F68541 | U.K. | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | 3TC+AZT+NFV | 198 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M184V | V21VI, V35T, E36A, T39E, S48T, D121H, K122E, K173T, Q174K, D177E, Q207E, R211K, F214FL, V245Q, A272P, K277R, T286A, E291D, V292I, I293V, V317A, I326V |
| >F68541| codons 1-333 PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL HEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPEIVI YQYVDDLYVGSDLEIGQHRTKIEELREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGAYYDPSKDLVAEIQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46MI, L90M | T12S, I13V, I15V, L19I, K20T, E35X, M36I, R41K, H69K, T74AS, L89I, I93L |
| >F68541| codons 1-99 PQITLWQRPLVSVKVGGQITEALLDTGADDTVLEXINLPGKWKPKIIGGIGGFIKVRQYD QILIEICGKKAIGAVLVGPTPVNIIGRNIMTQLGCTLNF |
References
| Author | Title | Citation |
| Weber, J | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |