Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SWC-6089 | 6089-4951 | U.S. | 2002 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI+ IDV | 7 |
| 2 | IDV | 11 |
| 3 | IDV+ 3TC | 179 |
| 4 | IDV+ 3TC+ DDI | 13 |
| 5 | 3TC | 1 |
| 6 | 3TC+ APV | 33 |
| 7 | 3TC | 11 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L | S68G |
| >6089-4951| codons 34-80 LVEICTELEKEGKISKIGPENPYNTPVFAIKKKDGTKWRKLVDFREL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54L | L10LF | R57K, I62V, L63P, A71T, I85V |
| >6089-4951| codons 1-99 PQITLWQRPFVTIKIGGQLKEALLDTGADDTVLEEMNLPGRWKPKMIGGIGGFLKVKQYD QVPIEICGHKTIGTVLVGPTPVNIVGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |