Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 98BWMC12 | 98BWMC12 | Botswana | 1998 | HIV1 | C | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, L19I, K20R, M36L, N37S, L63P, H69K, L89M, I93L |
| >98BWMC12| codons 1-99 PQITLWQRPLVSIKIGGQIREALLDTGADDTVLEELSLPGRWKPKMIGGIGGFIKVRQYD QIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36A, T39E, S48T, K122E, D123G, K166R, K173A, D177E, E194D, T200A, Q207I, V241I, V245Q, K259R, A272S, K277R, T286A, E291D, V292I, I293V, Q334Y, G335D, W337R, R356K, G359T, T369A, T377Q, K390R, A400T, E404D, V435A, F440L, R461K, D471E, Q480H, H483Q, L491S, S519N, K530R, A534S, A554S | P59S |
| >98BWMC12| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTSV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRAQNPEIVI YQYMDDLYVGSDLDIGQHRAKIEELRIHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT IQPIQLPEKDSWTVNDIQRLVGKLNWASQIYSGIKVRQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGYDQRTYQIYQEPFKNLKTGKYAKMRTA HTNDVKQLAEAVQKIAQESIVIWGKTPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIAGAETLYVDGAANRETKLGKAGYVTDKGRQKVVSLTETTNQKTELH AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKERVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| E10D, D25E, V31I, M50I, I84M, P90T, L101I, T112V, T124G, T125A, K136Q, V165I, V201I, L234V, E246D, D278A | S283G |
| >98BWMC12| codons 1-288 FLDGIDKAQDEHEKYHSNWRAMASEFNLPPIVAKEIVASCDKCQLKGEAIHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYMEAEVITAETGQETAYFILKLAGRWPVKVIHTDNGSN FTSGAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQIRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPVWKGPAK LLWKGDGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGADCVAGRQDED |
References
| Author | Title | Citation |
| Novitsky, V | Human immunodeficiency virus type 1 subtype C molecular phylogeny: consensus sequence for an AIDS vaccine design? | J Virol, 2002 |