Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 99BW4754 | 99BW4754 | Botswana | 1999 | HIV1 | C | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, E35D, M36I, R41K, L63H, H69K, K70R, L89M, I93L |
| >99BW4754| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QIHIEICGKRAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36A, T39E, V118I, K122E, D123N, I135T, E138A, I142V, K173A, T200A, E204K, Q207E, F214L, V245L, D250E, A272P, K275Q, T286A, E291D, V292I, I293V, Q334N, R356K, G359T, T369A, I375V, T377I, T386I, K390R, A400T, E404D, A437V, E449D, D471E, L491P, S519N, E529K, A534S, A554S, V559I | L234P |
| >99BW4754| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DENFRKYTAFTIPSTNNATPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPDIVI YQYMDDLYVGSDLEIGQHRAKIEKLREHLLRWGLTTPDKKHQKEPPFLWMGYEPHPDKWT VQPILLPEKESWTVNDIQKLVGKLNWASQIYPGIQVKQLCKLLRGAKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGNGQWTYQIYQEPFKNLKTGKYAKMRTA HTNDVKQLAEAVQKVAIESIVIWGKIPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPIVGVETFYVDGAANRDTKLGKAGYVTDRGRQKVVSLTETTNQKTELQ AIHLALQDSGPEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLIKKKKVYLSWVPAHK GIGGNEQVDKLVSSGIRKIL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| G4E, E10D, D25E, S39C, L45Q, M50I, F100Y, L101I, T125A, K136Q, V201I, T206S, K211R, T218I, L234I, N254K, R269K | S283G |
| >99BW4754| codons 1-288 FLDEIDKAQDEHEKYHSNWRAMASEFNLPPVVAKEIVACCDKCQQKGEAIHGQVDCSPGI WQLDCTHLEGKIILVAVHVASGYIEAEVIPAETGQETAYYILKLAGRWPVKTIHTDNGSN FTSTAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIASDIQTRELQKQIIKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDKSDIKVVPRRKAKIIKDYGKQMAGDDCVAGRQDED |
References
| Author | Title | Citation |
| Novitsky, V | Human immunodeficiency virus type 1 subtype C molecular phylogeny: consensus sequence for an AIDS vaccine design? | J Virol, 2002 |