Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 00BW1686 | 00BW1686 | Botswana | 2000 | HIV1 | C | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I15V, L19V, M36I, N37S, R41K, L63S, H69K, K70R, L89M, I93L |
| >00BW1686| codons 1-99 PQITLWQRPLVTIKVGGQVKEALLDTGADDTVLEEISLPGKWKPKMIGGIGGFIKVRQYD QISIEICGKRAIGTVLVGPTPVNIIGRNMLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36A, T39E, S48T, K122E, D123S, I135R, S163T, K173A, D177E, T200A, Q207D, R211K, P243T, V245Q, E248T, D250E, A272S, E291D, V292I, I293V, Q334H, G335D, R356K, G359T, K366R, T377M, I380V, K390R, A400T, T403A, E404D, L452A, V467I, L469I, D471E, H483Q, L491S, S519N, K527N, K530R, A534S, A554N |
| >00BW1686| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEEMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSRNNETPGIRYQYNVLPQGWKGSPAIFQSTMTKILEPFRAQNPEIVI YQYMDDLYVGSDLEIGQHRAKIEELRDHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQTIQLPTKESWTVNDIQKLVGKLNWASQIYSGIKVKQLCKLLRGTKALTDIVPLTEEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGHDQWTYQIYQEPFKNLKTGKYAKMRTA HTNDVRQLTEAVQKIAMESVVIWGKTPKFRLPIQKETWETWWADYWQATWIPEWEFVNTP PLVKLWYQLEKEPIVGAETFYVDGAANRETKAGKAGYVTDRGRQKVISITETTNQKTELQ AIQLALQDSGSEVNIVTDSQYALGIIQAQPDKSESELVNQIIEQLINKERVYLSWVPAHK GIGGNEQVDKLVSNGIRKVL |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| D25E, M50I, I72V, F100Y, L101I, T112I, T124A, T125A, K136Q, L172H, I182V, V201I, L234I, D278A | S283G |
| >00BW1686| codons 1-288 FLDGIDKAQEEHEKYHSNWRAMASEFNLPPVVAKEIVASCDKCQLKGEAIHGQVDCSPGI WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYYILKLAGRWPVKIIHTDNGSN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHHKTAVQMAV FVHNFKRKGGIGGYSAGERIIDIIATDIQTKELQKQITKIQNFRVYYRDSRDPIWKGPAK LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGADCVAGRQDED |
References
| Author | Title | Citation |
| Novitsky, V | Human immunodeficiency virus type 1 subtype C molecular phylogeny: consensus sequence for an AIDS vaccine design? | J Virol, 2002 |