Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| 00BW1795 | 00BW1795 | Botswana | 2000 | HIV1 | C | PBMC | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E36A, T39E, E40D, S48T, V118I, K122E, D123G, E138A, K166R, K173T, D177E, T200A, E204K, Q207E, R211K, F214L, A272P, K277T, T286A, E291D, V292I, I293V, E297D, Q334H, G335D, R356K, M357R, G359T, T377L, T386I, K390R, A400T, E404D, I434V, V435A, A437V, L452M, V466I, V467I, D471E, T477A, Q480H, H483Q, L491P, K527N, K530R, A534S, A554S |
| >00BW1795| codons 1-560 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEDMEKEGKITKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DEGFRKYTAFTIPSINNATPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRTQNPEIVI YQYMDDLYVGSDLEIGQHRAKIEKLREHLLKWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVTQLCKLLRGAKALTDIVPLTDEAE LELAENREILKEPVHGVYYDPSKDLIAEIQKQGHDQWTYQIYQEPFKNLKTGKYAKRRTA HTNDVKQLTEAVQKIALESIVIWGKIPKFRLPIQKETWETWWTDYWQATWIPEWEFVNTP PLVKLWYQLEKEPVAGVETFYVDGAANRETKMGKAGYVTDRGRQKIISLTETTNQKAELH AIQLALQDSGPEVNIVTDSQYALGIIQAQPDKSESELVSQIIEQLINKERVYLSWVPAHK GIGGNEQVDKLVSSGIRKVL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12S, I15V, L19I, E35D, M36I, R41K, Q61H, L63P, H69K, K70R, L89M, I93L | T96I |
| >00BW1795| codons 1-99 PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD HIPIEICGKRAIGTVLVGPTPVNIIGRNMLTQLGCILNF |
Integrase Sequence
| INIMajorDRMs | INIMinorDRMs | Polys | UnusualMuts |
| S24N, D25E, V31I, M50I, I73V, I84L, A91T, F100Y, L101I, T112V, T124A, T125A, K136Q, V201I, K211R, T218I, S230N, L234I, I251L, D256E, A265V, D278A | S283G |
| >00BW1795| codons 1-288 FLDGIDKAQEEHEKYHSNWRAMANEFNLPPIVAKEIVASCDKCQLKGEAIHGQVDCSPGI WQLDCTHLEGKIVLVAVHVASGYLEAEVIPTETGQETAYYILKLAGRWPVKVIHTDNGSN FTSAAVKAACWWAGIQQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV FIHNFKRKGGIGGYSAGERIIDIIATDIQTRELQKQIIKIQNFRVYYRDNRDPIWKGPAK LLWKGEGAVVLQDNSEIKVVPRRKVKIIRDYGKQMAGADCVAGRQDED |
References
| Author | Title | Citation |
| Novitsky, V | Human immunodeficiency virus type 1 subtype C molecular phylogeny: consensus sequence for an AIDS vaccine design? | J Virol, 2002 |