<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SA77_DR19 SA77_DR19 South Africa 2002 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 EFV+ AZT+ DDI NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, L210W, T215Y D67E K101E, V106M, G190A F227FL V8VA, V35I, T39E, E53D, T69S, K122E, D123S, S162C, E169A, K173T, Q174K, D177E, T200A, Q207E, R211K, V245Q, D250DE, A272P, K277KR, E291D, V292VI  
>SA77_DR19| codons 1-333
PISPIETAPVKLKPGMDGPKVKQWPLTEEKIKALIEICEELEKEGKISKIGPDNPYNTPV
FAIKKKESSKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLEKKKSMTVLDVGDAYFSVPL
DESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILAPFRTKNPEIVI
YQYMDDLYVASDLEIGQHRAKIEELREHLWKWGFYTPDKKHQKEPPLLWMGYELHPDKWT
VQPIQLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGTKALTDIIPLTEEAE
LELAENREILKEPVHGVYYDPSKDLIAEIQKQG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12S, I15V, L19I, M36I, R41K, D60E, Q61E, L63P, H69K, L89M, I93L  
>SA77_DR19| codons 1-99
PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYE
EIPIEICGKKAIGTVLVGPTPVNIIGRNMLTQLGCTLNF

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005