Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SA75_DR16 | SA75_DR16 | South Africa | 2002 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NFV+ ABC+ AZT+ 3TC | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, T69D, M184V, L210W, T215F | A98G | V35T, T39E, E44D, S48T, E53D, V111I, V118VI, D121DG, K122E, D123S, E138EA, K173A, Q174K, D177E, G196E, T200A, E203V, Q207E, H208Y, R211K, V245Q, E248D, A272P, K277R, T286A, E291D, V292I, I293V |
| >SA75_DR16| codons 1-310 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICEELEKDGKITKIGPDNPYNTPV FAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHPGGLKKKKSVTVLDIGDAYFSIPL GESFRKYTAFTIPSINNATPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEIVI YQYVDDLYVGSDLEIEQHRAKIVELREYLWKWGFFTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTEEAE LELAENREIL |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| D30N | L10F, V32VA, N88D | I15IL, G16E, L19I, E35D, M36IV, R41K, Y59YF, Q61E, I62IV, H69K, T74S, L89M, I93L, N98K |
| >SA75_DR16| codons 1-99 PQITLWQRPFVTIKLEGQIKEALLDTGADNTALEDINLPGKWKPKMIGGIGGFIKVRQFD EVLIEICGKKAIGSVLVGPTPVNIIGRDMLTQLGCTLKF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |