<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
RenG12181 RenG12181 Brazil 2009 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 PI+RTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I, I47V, I54V, V82A, L90M L33LF, F53L, G73S L10V, I15V, L19I, K20R, E34EQ, E35D, M36I, R41K, K43I, K55R, R57K, Q61H, I62V, L63P, A71T, I72T, I85V, Q92K  
>RenG12181| codons 4-99
TLWQRPVVTIKVGGQIREALLDTGADDTVFQDINLPGKWIPKIVGGIGGLVRVKQYDHVP
IEICGHKTTSTVLVGPTPANIVGRNLMTKIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, L74I, L210W, T215Y V75S, K219R     T39K, K43E, E44D, T107S, V111I, V118I, D121H, K122E, I178M, T200A, E203K, Q207E, H208Y, R211K, K223E, L228H, Q242H, V245E  
>RenG12181| codons 38-247
CKELEEDGKISKIGPENPYNTPVFAIKKKNSTKWRKISDFRELNKRTQDFWEVQLGIPHP
AGLKKKKSVSVLDIGDAYFSIPLHEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSP
AIFQSSMTKILEPFRKQNPDMVIYQYMDDLYVGSDLEIGQHRAKIKELREYLWKWGFYTP
DRKHQEEPPFHWMGYELHPDKWTVHPIELP

References
Author Title Citation
Diaz, RS The virological and immunological characteristics of the HIV-1-infected population in Brazil: from initial diagnosis to impact of antiretroviral use. PLoS ONE, 2015