Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| A119 | AF357718 | U.S. | 1998 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ DDI | 51 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K70R, T215F | D67AT, K219E | V108VI | T69N, D123E, D177E, I178V, I195IT, I202V, Q207E, R211K, V241I, A272S, K277KR, K281R, T286A, I293IV, E297K |
| >AF357718| codons 1-321 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALVEICTEMEKEGKISKIGPENPYNTPV FAIKKKASNRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTILDVGDAYFSVPL DKEFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPEVVI YQYMDDLYVGSDLETGQHRTKVEELREHLLKWGFFTPDEKHQKEPPFLWMGYELHPDKWT IQPIVLPEKDSWTVNDIQKLVGKLNWASQIYSGIKVRQLCRLLRGAKALTEVVPLTKEAE LELAENREILKEPVHGVYYDP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10M, N37S, R57K, L63A, C67D, I93L |
| >AF357718| codons 1-99 PQITLWQRPMVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVKQYD QIAIEIDGHKAIGTVLVGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Eshleman, SH | Analysis of human immunodeficiency virus type 1 drug resistance in children receiving nucleoside analogue reverse-transcriptase inhibitors plus nevirapine, nelfinavir, or ritonavir (Pediatric AIDS Clinical Trials Group 377). | J Infect Dis, 2001 |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |