Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SE561 | SE561 | Uganda | 1998 | HIV1 | D | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | 52 |
| 2 | NVP | 1 |
| 3 | None | 8 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13IV, K14KN, L19LI, K20KR, E35D, M36I, N37DE, R41K, H69K, K70R, L89M |
| >SE561| codons 1-99 PQITLWQRPLVTVNIGGQIREALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| E6X, V35T, K49KR, V60I, D121H, K122E, D123S, I135T, I142V, K166R, K173A, Q174K, D177E, T200I, Q207E, R211K, V245K, D250E, A272P, K277R, L282C, I293V | K11D |
| >SE561| codons 1-321 PISPIXTVPVDLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISRIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL HESFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTRILEPFRAKNPEIVI YQYMDDLYVGSDLEIGQHRIKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIKLPEKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKCLRGTKALTEVVPLTEEAE LELAENREILKEPVHGVYYDP |
References
| Author | Title | Citation |
| Eshleman, SH | Comparison of nevirapine (NVP) resistance in Ugandan women 7 days vs. 6-8 weeks after single-dose nvp prophylaxis: HIVNET 012. | ARHR, 2004 |
| Eshleman, SH | Impact of human immunodeficiency virus type 1 (hiv-1) subtype on women receiving single-dose nevirapine prophylaxis to prevent hiv-1 vertical transmission (HIV network for prevention trials 012 study). | J Infect Dis, 2001 |
| Eshleman, SH | Identification of Ugandan HIV type 1 variants with unique patterns of recombination in pol involving subtypes A and D. | ARHR, 2002 |