Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SE599 | SE599 | Uganda | 1998 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | 52 |
| 2 | NVP | 1 |
| 3 | None | 8 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, E40D, I50V, K122E, D123S, I135T, I142T, K173S, D177E, V179I, Q207A, R211S, F214L, V245Q, A272P, E291D, I293V, P294PT, L310I, E312D |
| >SE599| codons 1-321 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTDMEKEGKISKVGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGTRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSQNPEIII YQYMDDLYVGSDLEIGQHRTKIEELRAHLLSWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDVVTLTEEAE LELAENREIIKDPVHGVYYDP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10LV, I13V, E35D, M36I, R41K, R57K, L63M, H69R |
| >SE599| codons 1-99 PQITLWQRPVVTVKIGGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QIMIEICGRKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF |
References
| Author | Title | Citation |
| Eshleman, SH | Comparison of nevirapine (NVP) resistance in Ugandan women 7 days vs. 6-8 weeks after single-dose nvp prophylaxis: HIVNET 012. | ARHR, 2004 |
| Eshleman, SH | Impact of human immunodeficiency virus type 1 (hiv-1) subtype on women receiving single-dose nevirapine prophylaxis to prevent hiv-1 vertical transmission (HIV network for prevention trials 012 study). | J Infect Dis, 2001 |
| Eshleman, SH | Identification of Ugandan HIV type 1 variants with unique patterns of recombination in pol involving subtypes A and D. | ARHR, 2002 |