Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SE649 | SE649 | Uganda | 1998 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | 52 |
| 2 | NVP | 1 |
| 3 | None | 8 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| P4PH, E6ED, K11KT, K20R, V35T, T39L, V60I, D121Y, K122E, D123G, I135T, K173S, Q174K, D177E, V179I, Q207A, R211S, V245E, D250E, K281R, T286A, A288S, E291D, I293V, E297K, E312D, V317A |
| >SE649| codons 1-321 PISHIDTVPVTLKPGMDGPRVKQWPLTEEKIKALTEICLEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL YEGFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPEIII YQYMDDLYVGSDLEIGQHRTKIEELRAHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGAKSLTDVVPLTKEAE LELAENREILKDPVHGAYYDP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13IV, L19LI, E35D, M36I, R41K, K45R, R57K, L63S, H69K, L89M |
| >SE649| codons 1-99 PQITLWQRPLVTVKIGGQIKEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVKQYD QISIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Eshleman, SH | Identification of Ugandan HIV type 1 variants with unique patterns of recombination in pol involving subtypes A and D. | ARHR, 2002 |
| Eshleman, SH | Impact of human immunodeficiency virus type 1 (hiv-1) subtype on women receiving single-dose nevirapine prophylaxis to prevent hiv-1 vertical transmission (HIV network for prevention trials 012 study). | J Infect Dis, 2001 |