Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SE652 | SE652 | Uganda | 1998 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | 52 |
| 2 | NVP | 1 |
| 3 | None | 8 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K11T, K20R, V21I, V35T, T39K, V60I, K103Q, K122E, D123N, K173S, D177EG, V179I, D192N, T200A, I202V, Q207A, R211RK, V245Q, E248D, A272P, K281R, T286A, E291D, I293V, P294A, E312D, P321S |
| >SE652| codons 1-321 PISPIETVPVTLKPGMDGPRIKQWPLTEEKIKALTEICKEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKQKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSQNPEIII YQYMDDLYVGSNLEIGQHRAKVEELRAHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGAKALTDVVALTEEAE LELAENREILKDPVHGVYYDS |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, E35D, M36I, R41K, K45R, R57K, L63P, H69K, K70KR, L89M |
| >SE652| codons 1-99 PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVKQYD QIPIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Eshleman, SH | Comparison of nevirapine (NVP) resistance in Ugandan women 7 days vs. 6-8 weeks after single-dose nvp prophylaxis: HIVNET 012. | ARHR, 2004 |
| Eshleman, SH | Impact of human immunodeficiency virus type 1 (hiv-1) subtype on women receiving single-dose nevirapine prophylaxis to prevent hiv-1 vertical transmission (HIV network for prevention trials 012 study). | J Infect Dis, 2001 |
| Eshleman, SH | Identification of Ugandan HIV type 1 variants with unique patterns of recombination in pol involving subtypes A and D. | ARHR, 2002 |