<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SE655 SE655 Uganda 1998 HIV1 A Plasma None

Treatment History
Order Regimen Weeks
1 None 52
2 NVP 1
3 None 8

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  L33F I13V, K14R, E35D, M36I, R41K, R57K, H69K, L89M  
>SE655| codons 1-99
PQITLWQRPLVTVRIGGQLKEALLDTGADDTVFEDINLPGKWKPKMIGGIGGFIKVKQYD
QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K20R, V21I, V35T, T39G, D121Y, K122E, D123DG, I135T, S162SC, T165I, E169D, Q207G, R211K, V245M, D250E, T286A, E291D, V292VI, I293V, K311R  
>SE655| codons 1-321
PISPIETVPVKLKPGMDGPRIKQWPLTEEKIKALTEICGEMEKEGKISKIGPENPYNTPV
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
YEGFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMIKILDPFRKQNPDIVI
YQYMDDLYVGSDLEIGQHRTKIEELRGHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIMLPEKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVPLTEEAE
LELAENREILREPVHGVYYDP

References
Author Title Citation
Eshleman, SH Identification of Ugandan HIV type 1 variants with unique patterns of recombination in pol involving subtypes A and D. ARHR, 2002
Eshleman, SH Impact of human immunodeficiency virus type 1 (hiv-1) subtype on women receiving single-dose nevirapine prophylaxis to prevent hiv-1 vertical transmission (HIV network for prevention trials 012 study). J Infect Dis, 2001