Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SE73 | SE73 | Uganda | 1998 | HIV1 | C | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | 52 |
| 2 | NVP | 1 |
| 3 | None | 8 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K103KN | V35T, E36A, T39E, E40D, K43R, S48E, E53D, K101Q, K122E, D123G, E138A, S162Y, K173A, D177G, V179I, G196E, T200A, Q207D, V245Q, A272P, K277R, T286A, E291D, V292I, K311R | T253TP |
| >SE73| codons 1-321 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTAICEDMEREGKIEKIGPDNPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLQKNKSVTVLDVGDAYFSVPL DEGFRKYTAFTIPSINNATPGIRYQYNVLPQGWKGSPAIFQYSMTKILEPFRAQNPGIII YQYMDDLYVGSDLEIEQHRAKIEELRDHLLRWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWPVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIIPLTEEAE LELAENREILREPVHGVYYDP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T12TS, K14R, I15V, N37K, R41N, L63P, H69K, V77I, I93L |
| >SE73| codons 1-99 PQITLWQRPLVSIRVGGQLKEALLDTGADDTVLEEMKLPGNWKPKMIGGIGGFIKVRQYD QIPIEICGKKAIGTVLIGPTPVNIIGRNLLTQLGCTLNF |
References
| Author | Title | Citation |
| Eshleman, SH | Comparison of nevirapine (NVP) resistance in Ugandan women 7 days vs. 6-8 weeks after single-dose nvp prophylaxis: HIVNET 012. | ARHR, 2004 |
| Eshleman, SH | Identification of Ugandan HIV type 1 variants with unique patterns of recombination in pol involving subtypes A and D. | ARHR, 2002 |
| Eshleman, SH | Impact of human immunodeficiency virus type 1 (hiv-1) subtype on women receiving single-dose nevirapine prophylaxis to prevent hiv-1 vertical transmission (HIV network for prevention trials 012 study). | J Infect Dis, 2001 |
| Eshleman, SH | Survival of Ugandan infants with subtype A and D HIV-1 infection (HIVNET 012). | JAIDS, 2002 |