Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| SE592 | SE592 | Uganda | 1998 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | None | 52 |
| 2 | NVP | 1 |
| 3 | None | 8 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| E6N, V21I, V35T, T39K, V60I, K122E, D123N, I135T, K173S, Q174K, D177E, I178M, V179I, T200A, Q207E, R211RS, V245E, D250E, E291D, I293V, P294T |
| >SE592| codons 1-321 PISPINTVPVKLKPGMDGPKIKQWPLTEEKIKALTEICKEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPEMII YQYMDDLYVGSDLEIGQHRAKIEELREHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIELPEKESWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGTKALTDVVTLTEEAE LELAENREILKEPVHGVYYDP |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10LV, T12TA, I13V, I15IV, K20R, E35D, M36I, R41K, H69K, K70KR, L89M |
| >SE592| codons 1-99 PQITLWQRPVVAVKVGGQLREALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QILIEICGKRAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Eshleman, SH | Survival of Ugandan infants with subtype A and D HIV-1 infection (HIVNET 012). | JAIDS, 2002 |
| Eshleman, SH | Identification of Ugandan HIV type 1 variants with unique patterns of recombination in pol involving subtypes A and D. | ARHR, 2002 |
| Eshleman, SH | Impact of human immunodeficiency virus type 1 (hiv-1) subtype on women receiving single-dose nevirapine prophylaxis to prevent hiv-1 vertical transmission (HIV network for prevention trials 012 study). | J Infect Dis, 2001 |