Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| BR039 | 10000 | Brazil | 2000 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | RTV+ SQV+ D4T+ DDI | 52 |
| 2 | AZT+ NFV+ 3TC+ NVP | 32 |
| 3 | IDV+ D4T+ ABC+ RTV | 58 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| G48V, I54V, V82A | K43T | L10I, E35D, M36I, I62V, L63P, I64V, H69Q |
| >10000| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTVLEDINLPGRWTPKMIVGIGGFVKVRQYD QVPVEICGQKAIGTVLVGPTPANIIGRNLLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, L74I, L210W, T215Y | K219R | V106A | F227L | E28X, K43E, E44A, V118I, K122E, I178M, T200K, E203D, H208Y, R211K, H221Y | L12F, L26F |
| >10000| codons 9-239 PVKFKPGMDGPKVKQWPFTDEKIKALVEICTELEEAGKISKIGPENPYNTPVFAIKKKNS TKWRKIVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSATVLDVGDAYFSIPLDEDFRKYT AFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDMVIYQYMDDLY VGSDLEIGQHRKKIDELRQYLWKWGFYTPDRKYQKEPPLLWMGYELHPDKW |
References
| Author | Title | Citation |
| Gonzales, MJ | Protease and reverse transcriptase mutation patterns in HIV-1 isolates from heavily treated persons: comparison of isolates from northern California with isolates from other regions. | ARHR, 2003 |
| Rodrigues, R | Prevalence of ARV resistance mutations and impact of genotyping test in HIV patients with advance disease in Sao Paulo, Brazil. | J Clin Virol, 2005 |