Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL40184 | 68632 | Portugal | 2001 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | RTI | NA |
| 2 | D4T+DDC | 31 |
| 3 | ATV+DDC+TDF | 22 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L10IV, T12I, I13V, K14R, G16E, E35D, M36I, R41K, R57RK, H69K, L89M |
| >68632| codons 1-99 PQITLWQRPIVIVRIEGQLKEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVKQYD QILIEICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41ML, M184V, T215Y | K103N | V35X, E36D, K49KR, V60VI, S68SG, V90VI, D123E, I132IV, I135V, E138Q, S162A, K173T, Q174E, D177E, T200A, Q207X, V245Q, A272P, K275R, E291D, V292I, I293V, P294PT, E312N, I326V |
| >68632| codons 1-334 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALXDICTELEKEGKISRIGPENPYNTPI FAIKKKDGTKWRKLVDFRELNKRTQDFWEIQLGIPHPAGLKKNKSVTVLDVGDAYFSVPL DKEFRKYTAFTVPSVNNQTPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTENPEIVI YQYVDDLYVGSDLEIGQHRAKIEELRXHLLRWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIRVKQLCKLLRGTKALTDIVTLTEEAE LELAENREILKNPVHGVYYDPSKDLVAEIQKQGQ |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |