Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL28285 | 67988 | Portugal | 2001 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | EFV+ TDF+ D4T | NA |
| 2 | ATV+ IDV+ DDC+ AZT | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I84V, L90M | L33LF, L89V | L10V, I13V, K14R, G16E, K20IM, E35EG, M36I, R41K, Q61H, C67Y, G68D, H69K, A71T, I72R |
| >67988| codons 1-99 PQITLWQRPVVTVRIEGQLIEALLDTGADDTVFEGINLPGKWKPKMIGGIGGFIKVRQYD HILIEIYDKKTRGTVLVGPTPVNVIGRNVMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Q151M, M184MV | A62V, D67G, V75I, F116Y, K219E | Y181C | K11Q, A33V, V35T, E36D, K49R, V60I, S68G, D121H, K122E, D123S, I135V, S162A, K173T, Q174R, D177E, T200A, I202V, Q207E, R211K, F214L, V245K, A272P, K277R, T286A, A288T, E291D, V292I, I293V, P294T, S322T, I326V |
| >67988| codons 1-333 PISPIETVPVQLKPGMDGPKVKQWPLTEEKIKVLTDICTEMEKEGKISRIGPENPYNTPI FVIKKKGGTKWRKLIDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYYSVPL HESFRKYTAFTIPSVNNETPGIRYQYNVLPMGWKGSPAIFQASMTKILEPFRTRNPEIVI CQYVDDLYVGSDLEIGQHRAKVEELREHLLKWGLTTPDEKHQKEPPFLWMGYELHPDKWT VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKTLTDIVTLTEEAE LELAENREILKEPVHGVYYDPTKDLVAEIQKQG |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |