<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL38923 65841 Portugal 2001 HIV1 CRF02_AG Plasma None

Treatment History
Order Regimen Weeks
1 TDF+ DDC NA
2 SQV+ D4T+ AZT+ ATV NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46I   I13V, E35N, M36I, N37D, I64M, H69K, T74S, L89T  
>65841| codons 1-99
PQITLWQRPLVTVKIGGQLKEALLDTGADDTVLENIDLPGRWKPKIIGGIGGFIKVRQYD
QILMEICGKKAIGSVLVGPTPVNIIGRNTLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67DN, T215Y       S3ST, V35T, T39N, E44D, V60I, D121DN, K122E, D123S, K173A, Q174K, D177E, I178M, G196E, T200A, E204KN, Q207E, R211K, V245Q, P247A, E248D, S251H, A272P, T286A, E291D, V292I, I293V, P294V V111VG
>65841| codons 1-321
PITPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICNELEKDGKISKIGPENPYNTPI
FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDGGDAYFSVPL
NESFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAKNPEMVI
YQYMDDLYVGSDLEIEQHRAKIEKLREHLLKWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLADKDHWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVVLTEEAE
LELAENREILKEPVHGVYYDP

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005