Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL7434 | 61838 | Portugal | 2001 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | SQV+ EFV+ TDF+ DDC+ DDI+ D4T+ AZT | NA |
| 2 | ATV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| Y181C | V108VI | V21I, V35T, T39A, V60I, F87X, K122A, S134N, I135V, T139K, S162A, K173T, Q174E, D177E, Q197K, T200A, Q207E, R211K, V245Q, E248N, A272P, K277R, T286A, V292I, I293V, E297A, E300EK, E308EG, E312D |
| >61838| codons 1-317 PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTEICAEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDLWEVQLGIPHPAGLKKKKSVTILDVGDAYFSVPL DADFRKYTAFTIPNVNNEKPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTENPEIVI CQYMDDLYVGSDLEIGKHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPNKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTEIVPLTAEAK LELAENRGILKDPVHGV |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| T74P | I13V, I15V, K20I, M36I, R41K, I64M, H69K, K70R, L89M |
| >61838| codons 1-99 PQITLWQRPLVTVKVGGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QILMEICGKRAIGPVLVGPTPVNIIGRNMLTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |