<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL7434 61838 Portugal 2001 HIV1 CRF02_AG Plasma None

Treatment History
Order Regimen Weeks
1 SQV+ EFV+ TDF+ DDC+ DDI+ D4T+ AZT NA
2 ATV NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
    Y181C V108VI V21I, V35T, T39A, V60I, F87X, K122A, S134N, I135V, T139K, S162A, K173T, Q174E, D177E, Q197K, T200A, Q207E, R211K, V245Q, E248N, A272P, K277R, T286A, V292I, I293V, E297A, E300EK, E308EG, E312D  
>61838| codons 1-317
PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTEICAEMEKEGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDLWEVQLGIPHPAGLKKKKSVTILDVGDAYFSVPL
DADFRKYTAFTIPNVNNEKPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTENPEIVI
CQYMDDLYVGSDLEIGKHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPNKDSWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTEIVPLTAEAK
LELAENRGILKDPVHGV

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  T74P I13V, I15V, K20I, M36I, R41K, I64M, H69K, K70R, L89M  
>61838| codons 1-99
PQITLWQRPLVTVKVGGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QILMEICGKRAIGPVLVGPTPVNIIGRNMLTQIGCTLNF

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005