Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL9728 | 60099 | Portugal | 2001 | HIV1 | A | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | IDV+ DDI+ D4T | NA |
| 2 | ATV+ RTV+ IDV+ DDC+ AZT | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82A | L33I, F53L, N83D | L10Y, I13V, G16E, K20R, A22AV, E35DN, M36I, N37ND, R41RK, L63T, H69K, T74S, L89M, T91A |
| >60099| codons 1-99 PQITLWQRPYVTVKIEGQLREVLLDTGADDTVIEDIDLPGKWKPKMIGGIGGLVKVRQYD QITIEICGKKAIGSVLVGPTPADIIGRNMLAQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, L210W, T215Y | V35T, K43KE, V118VI, D121H, K122E, I135T, I142V, K173S, Q174K, D177E, T200A, Q207A, R211K, V245K, K281R, T286A, E291D, V292I, I293V, E297K, A304E, E312N, D320E, D324E, I329V |
| >60099| codons 1-332 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEEEGKISKIGPENPYNTPV FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL HEDFRKYTAFTIPSTNNETPGVRYQYNVLPQGWKGSPAIFQSSMTKILEPFRSKNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELRAHLWKWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIKLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCRLLRGAKALTDIVPLTKEAE LELEENREILKNPVHGVYYEPSKELIAEVQKQ |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |