<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL31154 59277 Portugal 2001 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 EFV+ DDC+ AZT NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        V35T, K43R, V60I, V90VI, A98S, K122E, D123G, I135V, K173R, Q174E, D177E, I195K, T200A, R211S, V245Q, E248AT, D250E, A272P, V276I, Q278H, T286A, E291D, V292I, I293V, E297A, D320E, D324E  
>59277| codons 1-324
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEREGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEIQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL
DEGFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRRENPEIVI
YQYMDDLYVGSDLEKGQHRAKIEELRQHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPAKESWTVNDIQKLVGKLNWASQIYPGIKIKHLCKLLRGAKALTDIVPLTAEAE
LELAENREILKEPVHGVYYEPSKE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
  V11VI I13V, K14R, K20I, E35D, M36I, R41K, K45R, H69K, V82I, L89M  
>59277| codons 1-99
PQITLWQRPLITVRIGGQLIEALLDTGADDTVLEDINLPGKWKPRMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005