Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL38970 | 68858 | Portugal | 2001 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ NFV+ SQV+ RTV+ 3TC+ DDI+ D4T | NA |
| 2 | RTV+ IDV+ DDI+ D4T | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54IV, L90LM | I13V, K14R, K20I, E35D, M36I, R41K, H69KR, V82I, L89M | A28Q |
| >68858| codons 1-99 PQITLWQRPLVTVRIGGQLIEALLDTGQDDTVLEDINLPGKWKPKMIGGIGGFVKVRQYD QILIEICGKKAIGTVLVGPTPINIIGRNMMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| V35T, T39TA, K43KR, V60I, A98S, D121DN, K122E, D123S, I135IT, K173T, Q174K, D177E, I178L, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, A288AG, E291D, V292I, I293IV, E297A, E328K, I329V, Q330QP |
| >68858| codons 1-333 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICAEMEREGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL NESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPELVI YQYMDDLYVGSDLEIGQHRAKIEELRKHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKGLTDIVPLTAEAE LELAENREILKEPVHGVYYDPSKDLIAKVPKQG |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |