Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| CA641 | CA3109 | U.S. | 1997 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT | 104 |
| 2 | AZT+DDI | 117 |
| 3 | 3TC+AZT | 31 |
| 4 | 3TC+AZT+IDV | 26 |
| 5 | 3TC+D4T+IDV | 27 |
| 6 | 3TC+D4T+RTV+SQV | 43 |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67DN, T69AD, M184V, L210W, T215Y | V35M, T39S, K43KE, E44D, V118I, K122E, V179VI, T200A, E203K, Q207D, H208Y, R211K, K223E, L228H, A272P, K277R |
| >CA3109| codons 1-278 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMEICSELEEDGKISKIGPENPYNTPV FAIKKKNSAKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRKQNPDIII YQYVDDLYVGSDLEIGQHRAKIKELRDYLWKWGFYTPDKKHQEEPPFHWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V32VI, M46MI, V82A, L90M | F53L | L10I, L33M, N37C, L63P, A71AV |
| >CA3108| codons 1-99 PQITLWQRPIVTIKIGGQLKEALLDTGADDTIMEEMCLPGRWKPKIIGGIGGLIKVRQYD QIPIEICGHKVIGTVLVGPTPANIIGRNLMTQIGCTLNF |
References
| Author | Title | Citation |
| Rhee, SY | HIV-1 Protease and Reverse Transcriptase Mutations: Correlations with Antiretroviral Therapy in Subtype B Isolates and Implications for Drug-Resistance Surveillance. | J Infect Dis, 2005 |