<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL8343 65230 Portugal 2002 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 AZT+DDC+IDV 60
2 DDC+3TC+NVP 100
3 3TC+EFV+APV+LPV 57

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
L74V, M184V   K103N V179VE V35T, K43R, V60VI, A98S, K122E, D123S, I135T, E138Q, K173I, Q174K, D177E, T200AV, Q207K, R211S, V245Q, E248D, D250E, A272P, K281KR, T286A, E291D, V292I, I293V, E297A, A304E, D320E, D324E, I329V, Q334L  
>65230| codons 1-335
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEREGKISKIGPENPYNTPI
FAIKKKDSTKWRKVVDFRELNKRTQDFWEVQLGIPHPSGLKKNKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNQTPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPEIEI
YQYVDDLYVGSDLEIGQHRAKIEELRKHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCRLLRGAKALTDIVPLTAEAE
LELEENREILKEPVHGVYYEPSKELIAEVQKQGLG

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005