Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL9219 | 65471 | Portugal | 2001 | HIV1 | B | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | IDV+ 3TC+ DDC | NA |
| 2 | NVP+ DDI+ AZT | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| V82T | K43T | L10IV, Q18QH, K20R, E35D, M36I, N37D, R41K, L63T, I64V, E65D, I72V, I93L |
| >65471| codons 1-99 PQITLWQRPIVTIKIGGHLREALLDTGADDTVLEDIDLPGKWTPKMIGGIGGFIKVRQYD QITVDICGHKAVGTVLVGPTPTNIIGRNLLTQLGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70KR, T215Y | Y181C, G190A | E6D, T7TA, K20R, D121Y, K122E, I135X, K166R, D177E, G196E, Q207D, L210LF, K277R, P294T, E297K, K311R, I329L |
| >65471| codons 1-334 PISPIDAVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL YEDFRKYTAFTIPSXNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPEIVI CQYMDDLYVASDLEIEQHRTKIEELRDHLFRWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGTKALTEVITLTKEAE LELAENREILREPVHGVYYDPSKDLIAELQKQGQ |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |