<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL9219 65471 Portugal 2001 HIV1 B Plasma None

Treatment History
Order Regimen Weeks
1 IDV+ 3TC+ DDC NA
2 NVP+ DDI+ AZT NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
V82T K43T L10IV, Q18QH, K20R, E35D, M36I, N37D, R41K, L63T, I64V, E65D, I72V, I93L  
>65471| codons 1-99
PQITLWQRPIVTIKIGGHLREALLDTGADDTVLEDIDLPGKWTPKMIGGIGGFIKVRQYD
QITVDICGHKAVGTVLVGPTPTNIIGRNLLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70KR, T215Y   Y181C, G190A   E6D, T7TA, K20R, D121Y, K122E, I135X, K166R, D177E, G196E, Q207D, L210LF, K277R, P294T, E297K, K311R, I329L  
>65471| codons 1-334
PISPIDAVPVKLKPGMDGPRVKQWPLTEEKIKALVEICTELEKEGKISKIGPENPYNTPV
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
YEDFRKYTAFTIPSXNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRKQNPEIVI
CQYMDDLYVASDLEIEQHRTKIEELRDHLFRWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIVLPEKDSWTVNDIQKLVGKLNWASQIYAGIKVRQLCKLLRGTKALTEVITLTKEAE
LELAENREILREPVHGVYYDPSKDLIAELQKQGQ

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005