Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL20533 | 64517 | Portugal | 2001 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | IDV+ NVP+ DDI+ D4T | NA |
| 2 | APV+ ABC+ 3TC+ AZT | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| G190A | E6D, K20R, V35T, T39G, V60I, K104KR, D121H, K122KE, K173A, D177E, V179VI, G196K, T200A, Q207E, R211K, V245MT, D250E, A272P, E291D, V292I, I293V, E297A, E312D, P321S, D324E |
| >64517| codons 1-334 PISPIDTVPVKLKPGMDGPRVKQWPLTEEKIKALTEICGEMEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKRSVTVLDVGDAYFSVPL HEDFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRAQNPEIII YQYMDDLYVASDLEIKQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT VQPIMLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGTKALTDIVPLTAEAE LELAENREILKDPVHGVYYDSSKELIAEIQKQGQ |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K20I, M36I, R41K, L63P, C67S, H69R, I72T, V82I, L89I |
| >64517| codons 1-99 PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD QIPIEISGRKATGTVLVGPTPINIIGRNILTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |