Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL31421 | 63409 | Portugal | 2001 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | IDV+ NVP+ 3TC+ DDC+ DDI+ D4T+ AZT | NA |
| 2 | LPV+ APV+ DDI+ D4T | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I13V, K14R, K20I, E35D, M36I, R41K, L63P, C67E, H69K, V82I, L89M |
| >63409| codons 1-99 PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QIPIEIEGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| K219KE | K103KN, Y181C | V35T, K43R, V60I, V90VI, A98S, V106VI, K122E, D123NS, K173IV, Q174K, D177E, I178IL, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, K275KQ, T286A, E291D, V292I, I293V, E297A, D324E, I329V, Q334L |
| >63409| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEREGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEIQLGIPHPSGLKKNKSITVLDVGDAYFSVPL DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPELVI CQYMDDLYVGSDLEIGQHRAKIEELRKHLLSWGFTTPDEKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIQVKQLCKLLRGAKALTDIVPLTAEAE LELAENREILKEPVHGVYYDPSKELIAEVQKQGLG |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |