Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL23972 | 63353 | Portugal | 2001 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NFV+ 3TC+ D4T | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, M184V | K11KR, E28A, V35T, V60VI, K122E, D123S, I135T, S162C, K173T, Q174K, D177E, T200A, Q207K, R211S, F214FL, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D324E, I329V |
| >63353| codons 1-333 PISPIETVPVRLKPGMDGPKVKQWPLTAEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQCSMTKILEPFRTKNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELRKHLLSWGLTTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE LELAENREILKEPVHGVYYDPSKELIAEVQKQG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | I13V, K14R, K20I, E35X, M36I, R41K, I62IV, I64IV, I66IF, H69K, K70KR, V82I, L89I, Q92QK, I93IL |
| >63353| codons 1-99 PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEXINLPGKWKPKMIGGIGGFIKVRQYD QVLVEFCGKRAIGTVLVGPTPINIIGRNIMTKLGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |