<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL38201 64222 Portugal 2001 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 DDI+ AZT+ SQV NA
2 IDV+ 3TC+ D4T NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46MI, I54V, V82M, L90M   I13AV, K14R, I15IV, K20I, E35D, M36I, N37D, R41K, L63LP, H69K, K70R, L89I  
>64222| codons 1-99
PQITLWQRPLVTARVGGQLIEALLDTGADDTVLEDIDLPGKWKPKIIGGIGGFVKVRQYD
QIPIEICGKRAIGTVLVGPTPMNIIGRNIMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, K70R, M184V, T215Y K219E     V35T, K43R, V60I, S68G, A98S, K122E, D123S, I135T, K173T, Q174K, D177G, T200A, Q207K, R211S, L228H, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, L301M, D320E, D324E, I329V  
>64222| codons 1-333
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEREGKISKIGPENPYNTPI
FAIKKKNGTRWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRTKNPGIVI
YQYVDDLYVGSDLEIGQHRAKIEELRKHLLSWGFYTPDEKHQKEPPFHWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE
MELAENREILKEPVHGVYYEPSKELIAEVQKQG

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005