Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL19454 | 63189 | Portugal | 2001 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | Unknown | 31 |
| 2 | ABC+EFV+LPV | 22 |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46L, G48GV, I54V, L90M | L89V | T4TS, L10LV, I13V, K14R, K20I, M36I, N37D, R41EK, I62V, H69K, A71V, T74S, V82X |
| >63189| codons 1-99 PQISLWQRPVVTVRIGGQLIEALLDTGADDTVLEEIDLPGEWKPKLIVGIGGFVKVRQYD QVLIEICGKKVIGSVLVGPTPXNIIGRNVMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70KR, L74V, L210W, T215Y | K103N, Y181C, G190A | F227FL | L34LI, V35T, T39L, V60I, A98S, K101KQ, K122E, D123NS, K173R, Q174N, D177E, T200A, Q207G, R211K, H221HY, K223KE, V245T, D250E, A272P, T286A, E291D, V292I, I293V, E297T, A304E |
| >63189| codons 1-318 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKAITEICLELEKEGKISKIGPENPYNTPI FAIKKKNSTRWRKVVDFRELNKRTQDFWEVQLGIPHPSGLQKNKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRRNNPEIVI CQYMDDLYVASDLEIGQHRAKIEELRGHLWKWGFYTPDKKYQEEPPLLWMGYELHPDKWT VQPITLPEKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTTEAE LELEENREILKEPVHGVY |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |