Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL25290 | 62869 | Portugal | 2001 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDC+ AZT | NA |
| 2 | SQV+ 3TC+ D4T | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, M184V, T215Y | K219E | V35T, V60I, S68G, A98S, K102R, K122E, D123S, I135V, K166R, K173T, Q174AE, D177E, T200A, Q207K, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D320E |
| >62869| codons 1-322 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEKEGKISKIGPENPYNTPI FAIKKKNGTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKRKKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQSSMTRILEPFRTANPEIVI YQYVDDLYVGSDLEIGQHRAKIEELRKHLLSWGFYTPDEKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE LELAENREILKEPVHGVYYEPS |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90M | I13V, K20I, E35D, M36I, N37NS, R41K, L63P, H69K, K70R, A71AV, V82I, L89M |
| >62869| codons 1-99 PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLEDISLPGKWKPKMIGGIGGFIKVRQYD QIPIEICGKRVIGTVLVGPTPINIIGRNMMTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |