Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL26473 | 63176 | Portugal | 2001 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NFV+ SQV+ RTV+ IDV+ EFV+ 3TC+ DDI+ AZT | NA |
| 2 | 3TC+ LPV+ ABC | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, L74V, M184V, T215F | K219Q | L100I, K103N | V35T, S48SL, V60I, A98S, K122E, D123S, I135T, K173I, Q174K, D177E, T200A, Q207K, R211S, D218DE, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, L301M |
| >63176| codons 1-319 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEKEGKILKIGPENPYNTPI FAIKKKNSTRWRKVVDFRELNKRTQDFWEVQLGIPHPSGIKKNKSVTVLDVGDAYFSVPL DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELRKHLLSWGFFTPEQKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE MELAENREILKEPVHGVYY |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, V82F, L90M | L89V | L10I, I13V, K14R, K20I, E35N, M36I, N37ND, R41K, L63P, H69K, A71V, Q92QK |
| >63176| codons 1-99 PQITLWQRPIVTVRIGGQLIEALLDTGADDTVLENIDLPGKWKPKMIGGIGGFVKVRQYD QIPIEICGKKVIGTVLVGPTPFNIIGRNVMTKIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |