<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL862 62513 Portugal 2001 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 DDC+ AZT NA
2 ATV+ IDV+ 3TC+ D4T NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
I54V, V82T, L90M   I13V, K14R, I15V, K20I, E35D, M36I, N37D, R41K, L63P, H69K, K70R, A71V, T74S, L89I  
>62513| codons 1-99
PQITLWQRPLVTVRVGGQLIEALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFVKVRQYD
QIPIEICGKRVIGSVLVGPTPTNIIGRNIMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, D67N, T69D, M184V, L210W, T215Y       K22R, V35K, T39TA, V60I, A98S, K122E, D123NS, I135L, S162SN, K173T, Q174K, T200A, Q207K, R211DN, V245Q, E248D, D250E, A272P, T286A, V292I, I293V, E297EA  
>62513| codons 1-319
PISPIETVPVKLKPGMDGPKVRQWPLTEEKIKALKEICAELEKEGKISKIGPENPYNTPI
FAIKKKNSDKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL
DENFRKYTAFTIPSLNNETPGIRYQYNVLPQGWKGSPAIFQNSMTKILEPFRTKNPDIVI
YQYVDDLYVGSDLEIGQHRAKIEELRKHLWDWGFYTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTEIVPLTAEAE
LELAENREILKEPVHGVYY

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005