<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL37132 61949 Portugal 2001 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 IDV+ 3TC+ AZT NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
D67DN, K70KR, M184V K219KQ     V35T, E40D, K43R, V60I, A98S, K122E, D123S, I135X, E138A, K173IT, Q174K, T200E, Q207K, R211S, F214FL, V245Q, E248D, D250E, A272P, T286A, E291D, V292VI, N306X  
>61949| codons 1-316
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTDMEREGKISKIGPENPYNTPI
FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSXNNATPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPDIVI
YQYVDDLYVGSDLEIGQHREKIEELRKHLLSWGLTTPDQKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIIPLTEEAE
LELAEKREILKEPVHG

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46MI, G48GV, I54V, V82T, I84IV, L90LM L89MV I13V, K14R, K20I, M36I, R41K, I66IF, H69K, A71V  
>61949| codons 1-99
PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEEINLPGKWKPKIIVGIGGFVKVRQYD
QILIEFCGKKVIGTVLVGPTPTNVIGRNMMTQIGCTLNF

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005