<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL36799 61175 Portugal 2001 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 NFV+ 3TC+ D4T NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46MI, I54IV, N88NS, L90LM   I13V, K14R, K20I, E35D, M36I, R41K, H69K, V82VI, L89M  
>61175| codons 1-99
PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEDINLPGKWKPKIIGGIGGFVKVRQYD
QILIEICGKKAIGTVLVGPTPINIIGRSMMTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V       V35T, K43R, K49R, V60I, A98AS, K102KR, K122E, D123S, I135T, K173I, Q174K, T200A, Q207K, R211S, F214FL, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A  
>61175| codons 1-318
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTEMEREGKISRIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKRKKSVTVLDVGDAYFSVPL
DESFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPDIVI
YQYVDDLYVGSDLEIGQHRAKIEELRKHLLSWGLTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE
LELAENREILKEPVHGVY

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005