Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL36069 | 59512 | Portugal | 2001 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDC+ AZT | NA |
| 2 | 3TC+ D4T+ NFV | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, M184V, T215Y | V35T, T39TI, V60I, A98S, K122KE, D123NS, I135T, K173I, Q174K, D177E, T200A, Q207E, R211S, V245Q, E248D, D250E, A272P, K277R, T286A, E291D, V292VI, I293V, E297A, D320E, D324E, I329V, Q334P |
| >59512| codons 1-335 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICIELEKEGKISKIGPENPYNTPI FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPEIVI YQYVDDLYVGSDLEIGQHRAKIEELREHLLSWGFYTPDKKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVRQLCKLLRGAKALTDIVPLTAEAE LELAENREILKEPVHGVYYEPSKELIAEVQKQGPG |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| I54V, L90M | I13V, K20I, E35N, M36I, N37ND, R41K, H69K, T74S, V82I, L89I |
| >59512| codons 1-99 PQITLWQRPLVTVKIGGQLIEALLDTGADDTVLENIDLPGKWKPKMIGGIGGFVKVRQYD QILIEICGKKAIGSVLVGPTPINIIGRNIMTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |