<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
PL17975 58686 Portugal 2001 HIV1 G Plasma None

Treatment History
Order Regimen Weeks
1 IDV NA
2 NVP+ 3TC+ AZT NA

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M184V   K103N   V35M, K43R, V60VI, A98S, K122E, D123S, I132IV, I135T, K173I, Q174K, D177E, T200A, R211S, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, L301M, D320E  
>58686| codons 1-320
PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALMEICTEMEREGKISKIGPENPYNTPI
FAIKKKDSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKNKSVTVLDVGDAYFSVPL
DESFRKYTAFTVPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFRIKNPEIVI
YQYVDDLYVGSDLEIGQHRAKIEELRQHLLSWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE
MELAENREILKEPVHGVYYE

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    I3IL, I13V, K14KR, K20I, E35D, M36I, N37D, R41K, H69K, V82I, L89M  
>58686| codons 1-99
PQLTLWQRPLVTVRIGGQLIEALLDTGADDTVLEDIDLPGKWKPKMIGGIGGFIKVRQYD
QILIEICGKKAIGTVLVGPTPINIIGRNMLTQIGCTLNF

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005