Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL35608 | 58508 | Portugal | 2001 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | IDV+ 3TC+ DDC+ D4T+ AZT | NA |
| 2 | NFV+ ABC+ D4T | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, I54V, V82A, L90M | I13V, K14KR, I15V, L19V, K20I, E35D, M36I, I64M, H69K, L89M |
| >58508| codons 1-99 PQITLWQRPLVTVRVGGQVIEALLDTGADDTVLEDINLPGRWKPKIIGGIGGFVKVRQYD QILMEICGKKAIGTVLVGPTPANIIGRNMMTQIGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| D67N, K70R, T215F | K219E | V21I, V35T, T39A, E53ED, V60I, K122E, D123N, I135V, S162A, K173T, Q174K, D177E, I178M, T200E, E203K, Q207E, V245Q, E248D, T286A, V292I, I293V, E297A |
| >58508| codons 1-307 PISPIETVPVKLKPGMDGPKIKQWPLTEEKIKALTEICAEMEKEGKISKIGPDNPYNTPI FAIKKKNSTRWRKLVDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEMVI YQYMDDLYVGSDLEIGQHREKIKELREHLLRWGFFTPDEKHQKEPPFLWMGYELHPDKWT VQPIQLPDKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTEIVPLTAEAE LELAENR |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |