Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL35484 | 58235 | Portugal | 2001 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | DDI+ AZT | NA |
| 2 | NFV+ 3TC+ D4T | NA |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46ML | T12A, I13V, K14R, K20T, E35D, M36I, R41K, I62V, L63P, H69K, A71T, T74S, V82I, L89X, I93M |
| >58235| codons 1-99 PQITLWQRPLVAVRIGGQLTEALLDTGADDTVLEDINLPGKWKPKLIGGIGGFIKVRQYD QVPIEICGKKTIGSVLVGPTPINIIGRNXLTQMGCTLNF |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, M184V, T215Y | K219Q | K20KR, V35L, K43R, V60I, A98S, D123DE, I135V, I142V, S162X, K173R, Q174K, D177E, G196E, T200A, Q207K, H208Y, R211N, D218E, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297T |
| >58235| codons 1-323 PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALLEICTELEREGKISKIGPENPYNTPI FAIKKKNSTKWRKLVDFRELNKRTQDFWEVQLGIPHPSGLKKKKSVTVLDVGDAYFSVPL DKEFRKYTAFTIPSVNNETPGVRYQYNVLPQGWKGSPAIFQXSMTKILEPFRRKNPEIVI YQYVDDLYVGSDLEIEQHRAKIEELRKYLLNWGFYTPEQKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTTEAE LELAENREILKEPVHGVYYDPSK |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |