Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL16925 | 58358 | Portugal | 2001 | HIV1 | CRF02_AG | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | NFV+ DDI | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, V75T, L210W, T215Y | K219KN | Y181C | V35KT, T39A, V60VI, S68G, V118VI, I135V, S162A, K173T, Q174K, D177E, I178M, T200A, Q207E, R211K, K223Q, P243S, V245E, T286A, E291D, V292I, I293V, P294T, S322A |
| >58358| codons 1-324 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALKEICAELEKEGKISKIGPENPYNTPI FAIKKKDGTKWRKLTDFRELNKRTQDFWEVQLGIPHPAGLKKKKSVTVLDVGDAYFSIPL DKDFRKYTAFTIPSVNNETPGIRYQYNVLPQGWKGSPAIFQASMTKILEPFRTKNPEMVI CQYMDDLYVGSDLEIGQHRAKIEELREHLWKWGFYTPDNKHQQEPPFLWMGYELHPDKWT VQSIELPEKDSWTVNDIQKLVGKLNWASQIYAGIKVKQLCKLLRGAKALTDIVTLTEEAE LELAENREILKEPVHGVYYDPAKD |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| M46I, L90M | L89V | L10V, I13V, K20V, M36I, R41K, L63P, H69K, K70R |
| >58358| codons 1-99 PQITLWQRPVVTVKIGGQLVEALLDTGADDTVLEEINLPGKWKPKIIGGIGGFIKVRQYD QIPIEICGKRAIGTVLVGPTPVNIIGRNVMTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |