Isolate Data
| Patient | Isolate | Region | Year | Species | Subtype | Source | Clone Method |
| PL405 | 55413 | Portugal | 2001 | HIV1 | G | Plasma | None |
Treatment History
| Order | Regimen | Weeks |
| 1 | AZT+ NFV+ SQV+ IDV+ NVP+ 3TC+ DDC+ DDI | NA |
| 2 | EFV+ DDC+ D4T | NA |
RT Sequence
| NRTIMajorDRMs | NRTIMinorDRMs | NNRTIMajorDRMs | NNRTIMinorDRMs | Polys | UnusualMuts |
| M41L, D67N, K70R, V75T, T215Y | K219E | K103N, Y181C, G190A | V35T, K43R, V60I, T69N, A98S, K101Q, K122E, D123N, I135T, R172RK, K173I, Q174K, D177E, I178IM, T200A, E203K, Q207E, R211NS, D218DE, V245Q, E248D, D250E, A272P, T286A, E291D, V292I, I293V, E297A, D324E |
| >55413| codons 1-324 PISPIETVPVKLKPGMDGPKVKQWPLTEEKIKALTEICTELEREGKISKIGPENPYNTPI FAIKKKNSNRWRKLTDFRELNKRTQDFWEVQLGIPHPSGLQKNKSVTVLDVGDAYFSVPL DENFRKYTAFTIPSTNNETPGIRYQYNVLPQGWKGSPAIFQSSMTKILEPFKIKNPEMVI CQYMDDLYVASDLEIGQHRAKIKELREHLLNWGFYTPEEKHQKEPPFLWMGYELHPDKWT VQPIQLPDKESWTVNDIQKLVGKLNWASQIYPGIKVKQLCKLLRGAKALTDIVPLTAEAE LELAENREILKEPVHGVYYDPSKE |
Protease Sequence
| PIMajorDRMs | PIMinorDRMs | Polys | UnusualMuts |
| L90LM | I13V, K14R, K20I, E35D, M36I, R41K, I62IV, H69K, V82I, L89M |
| >55413| codons 1-99 PQITLWQRPLVTVRIGGQLIEALLDTGADDTVLEDINLPGKWKPKMIGGIGGFIKVRQYD QVLIEICGKKAIGTVLVGPTPINIIGRNMMTQIGCTLNF |
References
| Author | Title | Citation |
| Non-B Workgroup | Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. | PLoS Med, 2005 |