<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
SP_LP3 SP_LP3 Spain 2001 HIV1 CRF02_AG Plasma None

Treatment History
Order Regimen Weeks
1 PI+ NNRTI+ NRTI NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
M46L   I13V, K14G, I15V, K20I, M36I, R41K, I64M, H69K, L89M  
>SP_LP3| codons 5-99
LWQRPLVTVGVGGQLIEALLDTGADDTVLEEINLPGKWKPKLIGGIGGFIKVRQYDQILM
EICGKKAIGTVLVGPTPVNIIGRNMLTQIGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
M41L, M184V   K103N   V35K, T39A, E53D, V60I, A98S, K122E, I135V, S162A, K173A, Q174K, D177E, T200A, Q207E, R211K  
>SP_LP3| codons 33-225
ALKEICAELEKEGKISKIGPDNPYNTPIFAIKKKDSTKWRKLVDFRELNKRTQDFWEVQL
GIPHPSGLKKNKSVTVLDVGDAYFSVPLDEDFRKYTAFTIPSVNNETPGIRYQYNVLPQG
WKGSPAIFQASMTKILEPFRAKNPEIVIYQYVDDLYVGSDLEIGQHRAKIEELREHLLKW
GFTTPDKKHQKEP

References
Author Title Citation
Holguin, A HIV-positive immigrants in the Canary Islands, Spain: Implications for public health in Europe. HIV Clin Trials, 2003
Holguin, A Heterogeneous nature of HIV-1 recombinants spreading in Spain. J Med Virol, 2005