<!--#if expr="$title" --> <!--#echo var="title" --> <!--#else --> HIV Drug Resistance Database <!--#endif -->
Stanford University HIV Drug Resistance Database - A curated public database designed to represent, store, and analyze the divergent forms of data underlying HIV drug resistance.

Isolate Data

Patient Isolate Region Year Species Subtype Source Clone Method
BE69 BE69 Belgium 2001 HIV1 C Plasma None

Treatment History
Order Regimen Weeks
1 None NA

Protease Sequence
PIMajorDRMs PIMinorDRMs Polys UnusualMuts
    T12TS, I15V, L19LI, M36I, R41K, L63P, H69K, V82I, L89X, I93L  
>BE69| codons 1-99
PQITLWQRPLVSIKVGGQIKEALLDTGADDTVLEEINLPGKWKPKMIGGIGGFIKVRQYD
QIPIEICGKKAIGTVLVGPTPINIIGRNXLTQLGCTLNF

RT Sequence
NRTIMajorDRMs NRTIMinorDRMs NNRTIMajorDRMs NNRTIMinorDRMs Polys UnusualMuts
        K20R, V35M, E36EA, T39E, S48T, K122E, D123DG, A158AS, K173A, Q174QK, D177E, G196K, T200A, Q207E, R211RK, V245Q, A272P, K277KR, L279M, T286TA, E291D, V292I, I293V, V317A E40E*, L80LP, Q91QH
>BE69| codons 1-324
PISPIETVPVKLKPGMDGPRVKQWPLTEEKIKALMAICE*MEKEGKITKIGPENPYNTPV
FAIKKKDSTKWRKLVDFREPNKRTQDFWEVHLGIPHPAGLKKKKSVTVLDVGDAYFSVPL
DEGFRKYTAFTIPSINNETPGIRYQYNVLPQGWKGSPSIFQSSMTKILEPFRAKNPEIVI
YQYMDDLYVGSDLEIKQHRAKIEELREHLLKWGFTTPDKKHQKEPPFLWMGYELHPDKWT
VQPIQLPEKDSWTVNDIQKLVGKLNWASQIYPGIKVRQMCKLLRGAKALTDIVPLTEEAE
LELAENREILKEPVHGAYYDPSKD

References
Author Title Citation
Non-B Workgroup Impact of HIV-1 subtype and antiretroviral therapy on protease and reverse transcriptase genotype: Results of a global collaboration. PLoS Med, 2005
Snoeck, J Rising prevalence of HIV-1 non-B subtypes in Belgium: 1983-2001. JAIDS, 2004